SARS-CoV-2 S1 (RBD) Gamma, P.1 (Brazil), GFP/His-Tag Size:100µg Proteolytic cleavage results in release

Proteolytic cleavage results in release of active TGF-β1 from LAP

the mutations L452R of the SARS-CoV-2 Spike S1 (RBD) may cause a stronger affinity of the spike protein to hACE2 resulting in higher transmission and eventually also in reduced neutralization

Sequence without tags (AA 105-250):MAVLTQKQKKQHSVLHLVPINATSKDDSDVTEVMWQPALRRGRGLQAQGYGVRIQDAGVYLLYSQVLFQDVTFTMGQVVSREGQGRQETLFRCIRSMPSHPDRAYNSCYSAGVFHLHQGDILSVIIPRARAKLNLSPHGTFLGFVKL

such as B cell lymphomas and leukemia

Test Cleavage

SARS-CoV-2 S1 (RBD) Gamma, P.1 (Brazil), GFP/His-Tag Size:100µg Proteolytic cleavage results in releaseRecombinant protein of the receptor binding domain (RBD), Mutant (K417T E484K N501Y) of SARS CoV 2 (COVID 19) Spike S1 from Wuhan pneumonia virus with C terminal His GFP Tag. The mutations K417T E484K N501Y are characteristic for the fast spreading SARS CoV 2 virus Gamma variant (P. 1 lineage) emerged in Brazil. These mutations are affecting the receptor binding domain (RBD) of the spike protein, which the virus uses to bind to human cells receptors