SARS-CoV-2 S1 (RBD) B.1.141/B.1.258 (Scotland/U.K.) Tags_Tag-free which results in increased transmissibility

which results in increased transmissibility of the SARS-CoV-2 virus

Heike Rübsamen

Dysregulation causes pathological conditions ranging from chronic inflammatory and autoinflammatory diseases to autoimmune syndromes

: P2020-021

Mutant (L452R-E484Q) of SARS-CoV-2 (COVID-2019) Spike S1 from Wuhan pneumonia virus with C-terminal Fc/His-Tag

SARS-CoV-2 S1 (RBD) B.1.141/B.1.258 (Scotland/U.K.) Tags_Tag-free which results in increased transmissibilityRecombinant protein of the receptor binding domain (RBD), Mutant (N439K) of SARS CoV 2 (COVID 2019) Spike S1 from Wuhan pneumonia virus with C terminal His Tag. The N439K mutation, lineage B. 1. 141 B. 1. 258 (Scotland UK), is known as the second common mutation in the RBD of SARS CoV 2 and binds with high affinity to human ACE2 receptor. The mutation may result in immune escape from a panel of neutralizing monoclonal antibodies and polyclonal sera of